Albinterferon alfa-2b
Albinterferon alfa-2b is a protein pharmaceutical. It is currently being investigated in clinical studies.
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460 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis c | D006526 | — | B19.2 | 15 | 39 | 50 | 28 | 37 | 157 |
| Hepatitis | D006505 | — | K75.9 | 13 | 35 | 44 | 30 | 37 | 148 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | 12 | 32 | 37 | 26 | 32 | 129 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 7 | 27 | 39 | 21 | 29 | 114 |
| Chronic hepatitis | D006521 | — | K73.9 | 8 | 11 | 15 | 8 | 5 | 44 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | 5 | 4 | 9 | 8 | 7 | 31 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 7 | 9 | 5 | 4 | 3 | 26 |
| Hepatitis b | D006509 | — | — | 4 | 3 | 8 | 5 | 7 | 25 |
| Infections | D007239 | EFO_0000544 | — | — | 8 | 4 | 3 | 4 | 17 |
| Lymphoma | D008223 | — | C85.9 | 1 | 3 | 3 | 2 | 2 | 11 |
Show 32 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Melanoma | D008545 | — | — | 20 | 29 | 18 | — | 6 | 68 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 6 | 19 | 2 | — | — | 24 |
| Neoplasms | D009369 | — | C80 | 9 | 6 | 1 | — | 1 | 16 |
| Leukemia | D007938 | — | C95 | 4 | 10 | 1 | — | 1 | 15 |
| Cutaneous malignant melanoma | D000096142 | — | — | 1 | 6 | 6 | — | 1 | 13 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 2 | 8 | 4 | — | — | 13 |
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 2 | 9 | 2 | — | — | 12 |
| Recurrence | D012008 | — | — | 7 | 8 | 3 | — | — | 11 |
| Polycythemia vera | D011087 | — | D45 | 1 | 3 | 6 | — | 1 | 10 |
| Multiple myeloma | D009101 | — | C90.0 | — | 6 | 4 | — | — | 9 |
Show 41 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 5 | 3 | — | — | 1 | 6 |
| Colorectal neoplasms | D015179 | — | — | 2 | 5 | — | — | 1 | 6 |
| Urinary bladder neoplasms | D001749 | — | C67 | 2 | 2 | — | — | 1 | 5 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 2 | 2 | — | — | — | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 4 | 3 | — | — | — | 4 |
| Glioma | D005910 | EFO_0000520 | — | 1 | 3 | — | — | — | 4 |
| Uveal neoplasms | D014604 | EFO_1001230 | — | — | 3 | — | — | 1 | 4 |
| Myeloproliferative disorders | D009196 | — | D47.1 | — | 3 | — | — | — | 3 |
| Triple negative breast neoplasms | D064726 | — | — | 3 | 1 | — | — | — | 3 |
| Neurofibroma | D009455 | EFO_0000622 | — | 1 | 2 | — | — | — | 3 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Breast carcinoma in situ | D000071960 | — | D05 | 1 | — | — | — | — | 1 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Gliosarcoma | D018316 | — | — | 1 | — | — | — | — | 1 |
| Ependymoma | D004806 | — | — | 1 | — | — | — | — | 1 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 1 | — | — | — | — | 1 |
| Subependymal glioma | D018315 | EFO_1001197 | — | 1 | — | — | — | — | 1 |
| Urethral neoplasms | D014523 | EFO_0003846 | — | 1 | — | — | — | — | 1 |
| Mesothelioma | D008654 | — | C45 | 1 | — | — | — | — | 1 |
| Aids-related opportunistic infections | D017088 | — | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Substance-related disorders | D019966 | EFO_0003890 | F13 | — | — | — | — | 2 | 2 |
| Virus diseases | D014777 | — | B34 | — | — | — | — | 2 | 2 |
| Intravenous substance abuse | D015819 | — | — | — | — | — | — | 1 | 1 |
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | — | — | — | 1 | 1 |
| Cone dystrophy | D000077765 | — | — | — | — | — | — | 1 | 1 |
| Cone-rod dystrophies | D000071700 | — | — | — | — | — | — | 1 | 1 |
| Ataxia | D001259 | — | R27.0 | — | — | — | — | 1 | 1 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | — | 1 | 1 |
| Cough | D003371 | — | R05 | — | — | — | — | 1 | 1 |
| Cerebellar ataxia | D002524 | — | — | — | — | — | — | 1 | 1 |
Show 36 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Albinterferon alfa-2b |
| INN | albinterferon alfa-2b |
| Description | Albinterferon (alb-IFN, trade name Albuferon) is a recombinant fusion protein drug consisting of interferon alpha (IFN-α) linked to human albumin. Conjugation to human albumin prolongs the half-life of the IFN-α to about 6 days, allowing to dose it every two to four weeks.
|
| Classification | Protein |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107842 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 4DVS4AG4DF (ChemIDplus, GSRS) |
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Safety
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12 adverse events reported
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