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Drug ReportsAlbinterferon alfa-2b
Albinterferon alfa-2b
Albinterferon alfa-2b is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Variants
Financial
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Events Timeline
5D
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YTD
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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Patent Expiration
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ATC Codes
L: Antineoplastic and immunomodulating agents
— L03: Immunostimulants
— L03A: Immunostimulants
— L03AB: Interferons
— L03AB12: Albinterferon alfa-2b
HCPCS
No data
Clinical
Clinical Trials
456 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HepatitisD006505HP_0012115K75.92045623452196
Hepatitis cD006526—B19.21942592945179
Hepatitis aD006506EFO_0007305B151842542946173
Chronic hepatitis cD019698EFO_0004220B18.21131452138135
Chronic hepatitisD006521—K73.910172010859
Hepatitis bD006509——55106932
Chronic hepatitis bD019694EFO_0004239B18.155106831
Hiv infectionsD015658EFO_0000764B207953426
CarcinomaD002277—C80.081532223
LeukemiaD007938—C9541341121
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MelanomaD008545——203018—669
Renal cell carcinomaD002292EFO_0000376—5192——23
Bcr-abl positive chronic myelogenous leukemiaD015464EFO_0000340—284——13
Myeloid leukemiaD007951—C92184——12
Kidney neoplasmsD007680EFO_0003865C64282——11
RecurrenceD012008——474——10
Communicable diseasesD003141——343—19
Polycythemia veraD011087—D45136——9
PolycythemiaD011086EFO_0005804D75.1136——9
Multiple myelomaD009101—C90.0—64——9
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Breast neoplasmsD001943EFO_0003869C5053——16
SarcomaD012509——22———4
Colorectal neoplasmsD015179——23——14
Pancreatic neoplasmsD010190EFO_0003860C2514———4
Ovarian neoplasmsD010051EFO_0003893C5643———4
Uveal neoplasmsD014604EFO_1001230——3——14
Triple negative breast neoplasmsD064726——31———3
NeurofibromaD009455EFO_0000622—12———3
Ovarian epithelial carcinomaD000077216——32———3
GliomaD005910EFO_0000520——3———3
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
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Healthy volunteers/patients———2————2
Breast carcinoma in situD000071960—D051————1
Urethral neoplasmsD014523EFO_0003846—1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
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Total
Substance-related disordersD019966EFO_0003890F13————22
Intravenous substance abuseD015819——————11
Macular degenerationD008268EFO_0001365H35.30————11
Cone dystrophyD000077765——————11
Cone-rod dystrophiesD000071700——————11
AtaxiaD001259—R27.0————11
Gastroesophageal refluxD005764EFO_0003948K21————11
CoughD003371HP_0012735R05————11
Cerebellar ataxiaD002524HP_0001251—————11
Bilateral vestibulopathyD000071699——————11
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAlbinterferon alfa-2b
INNalbinterferon alfa-2b
Description
Albinterferon (alb-IFN, trade name Albuferon) is a recombinant fusion protein drug consisting of interferon alpha (IFN-α) linked to human albumin. Conjugation to human albumin prolongs the half-life of the IFN-α to about 6 days, allowing to dose it every two to four weeks.
Classification
Protein
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL2107842
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID4DVS4AG4DF (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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12 adverse events reported
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